Deals on vacations and trips to Wayne County

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Wayne County flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.
Quality Inn Perryville I-55

Quality Inn Perryville I-55

2.5 out of 5
per person
Sep 4 - Sep 8
found 12 hours ago
Roundtrip flight included
Chicago (ORD) to Cape Girardeau (CGI)
This hotel features an outdoor pool and a gym. Enjoy the hot tub and free perks like daily breakfast and free self parking. The front desk is staffed around-the-clock and laundry facilities are on offer.
Rockwood Inn

Rockwood Inn

2 out of 5
per person
Sep 4 - Sep 8
found 12 hours ago
Roundtrip flight included
Chicago (ORD) to Cape Girardeau (CGI)
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. A garden and a picnic area are also provided.
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3 out of 5
per person
Sep 4 - Sep 8
found 12 hours ago
Roundtrip flight included
Chicago (ORD) to Cape Girardeau (CGI)
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like self-serve breakfast and free self parking.
Super 8 by Wyndham Perryville

Super 8 by Wyndham Perryville

2 out of 5
per person
Sep 4 - Sep 8
found 12 hours ago
Roundtrip flight included
Chicago (ORD) to Cape Girardeau (CGI)
This motel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like self-serve breakfast and free self parking.
Quality Inn

Quality Inn

2.5 out of 5
per person
Sep 4 - Sep 8
found 12 hours ago
Roundtrip flight included
Chicago (ORD) to Cape Girardeau (CGI)
An outdoor pool, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like English breakfast and WiFi in public areas. A computer station is provided and the front desk is staffed around-the-clock.

Top Wayne County hotels deals

Private lake, beach & hot tub, romantic getaway or family vaca

Private lake, beach & hot tub, romantic getaway or family vaca

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A hot tub is featured at this vacation home, along with laundry facilities.
Hot Tub
Washer
Sam A Baker State Park

Sam A Baker State Park

2 out of 5
5732 State Hwy Missouri 143, Patterson, MO
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This cabin includes a picnic area and barbecue grills. Take advantage of the free self parking.
Kitchen
Pet friendly
'The Lakehouse' Lovely Wappapello Country Home!

'The Lakehouse' Lovely Wappapello Country Home!

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This vacation home features laundry facilities.
Kitchen
Washer
Spacious & Secluded Shook Home w/ Private Hot Tub!

Spacious & Secluded Shook Home w/ Private Hot Tub!

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A hot tub is available at this vacation home.
Hot Tub
Kitchen
Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff

2.5 out of 5
3109 Oak Grove, Poplar Bluff, MO
Free Cancellation
Reserve now, pay when you stay
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This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like continental breakfast and free self parking.
Pool
Breakfast included
Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

2 out of 5
4101 Highway 67 N, Poplar Bluff, MO
Free Cancellation
Reserve now, pay when you stay
Get rates
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. Luggage storage is provided and the front desk is staffed around-the-clock.
Pet friendly
Parking included
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Photos of local treasures

Browse Wayne County vacation photos for more inspiration

Photo by Kimberly Falk
Photo by Kimberly Falk
Photo by Jonathan Khourie
Photo by Jonathan Khourie
Photo by JG Morris
Photo by JG Morris
Photo by Isaac Richardson
Photo by Isaac Richardson
Photo by Isaac Richardson
Photo by Isaac Richardson

Frequently asked questions

How much are vacation packages to Wayne County?
With a Travelocity vacation package, you can live it up in Wayne County for as low as $302. Flights, hotels and experiences --- we've got you covered. You'll save tons just for bundling together your bookings. With all of that taken care of before you even go, you can sit back, relax and not worry about a thing.
Where can I get the best vacation package deals for Wayne County?
For an excellent package deal to Wayne County, book with Travelocity. Choose from 400 airlines and 1,000,000 properties around the world to create your ultimate adventure --- you're spoiled for choice!
Why should I book my Wayne County vacation package via Travelocity?
By booking your flights, hotel, car rental and activities altogether, you'll save both time and money. All our bookings come with a dedicated team of experts available 24/7, and you'll know that you'll always be getting the best deal in town with our Price Match Guarantee. So, what's stopping you? Book the vacation of your dreams today and start packing!
Can I save on my Wayne County car rental if I book it with a hotel or flight?
Certainly. And our Wayne County vacation packages are the perfect way to do it. In just a few clicks you can save money and time by combining your bookings. Collect the keys to your rental car then set your own course. Looking for things to do? Add some activities or experiences to your package and make savings on those too.
Which airport is best for Wayne County?
Organizing where you step off the plane in Wayne County is a cinch --- most carriers jet in and out of Cape Girardeau Municipal Airport (CGI).
What is there to do in Wayne County?
A diverse and exciting destination, Wayne County boasts some wonderful tourist attractions. Lake Wappapello and Clearwater Lake are a couple of the most popular.